Gene name:
CREB1 (CREB;CREB2) ;
Protein name:
Cyclic AMP-responsive element-binding protein 1 (CREB-1;cAMP-responsive element-binding protein 1) ;
Alternative:
Cyclic AMP-responsive DNA-binding protein ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with PPRC1. Binds DNA as a dimer. This dimer is stabilized by magnesium ions. Interacts, through the bZIP domain, with the coactivators TORC1/CRTC1, TORC2/CRTC2 and TORC3/CRTC3. When phosphorylated on Ser-117, binds CREBBP. Interacts (phosporylated form) with TOX3. Binds to HIPK2.
Function:
This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Implicated in synchronization of circadian rhythmicity.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MESGAENQQS | GDAAVTEAES | QQMTVQAQPQ | IATLAQVSMP | AAHATSSAPT |
100:
VTLVQLPNGQ | TVQVHGVIQA | AQPSVIQSPQ | VQTVQISTIA | ESEDSQESVD |
150:
SVTDSQKRRE | ILSRRPSYRK | ILNDLSSDAP | GVPRIEEEKS | EEETSAPAIT |
200:
TVTVPTPIYQ | TSSGQYIAIT | QGGAIQLANN | GTDGVQGLQT | LTMTNAAATQ |
250:
PGTTILQYAQ | TTDGQQILVP | SNQVVVQAAS | GDVQTYQIRT | APTSTIAPGV |
300:
VMASSPALPT | QPAEEAARKR | EVRLMKNREA | ARECRRKKKE | YVKCLENRVA |
325:
VLENQNKTLI | EELKALKDLY | CHKSD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
ELISA Kit for Bovine CREB-1
ELISA Kit for Bovine CREB-1
ELISA Kit for Bovine CREB-1
ELISA Kit for Bovine CREB-1
CLIA Kit for Bovine CREB-1
CLIA Kit for Bovine CREB-1
CLIA Kit for Bovine CREB-1
CLIA Kit for Bovine CREB-1
Polyclonal Antibody for Bovine CREB-1
Polyclonal Antibody for Bovine CREB-1
Polyclonal Antibody for Bovine CREB-1
Polyclonal Antibody for Bovine CREB-1
Monoclonal Antibody for Bovine CREB-1
Monoclonal Antibody for Bovine CREB-1
Monoclonal Antibody for Bovine CREB-1
Monoclonal Antibody for Bovine CREB-1
Protein for Bovine CREB-1
Protein for Bovine CREB-1
Protein for Bovine CREB-1
Protein for Bovine CREB-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Thymus .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-117